The Power of Precision Medicine in Advanced Non-Small Cell Lung Cancer: Focus on Targeting MET Alterations
ACE Oncology Satellite Symposium

The Power of Precision Medicine in Advanced Non-Small Cell Lung Cancer: Focus on Targeting MET Alterations

In the era of precision medicine, detecting genomic alterations is the first priority and guiding principle for personalized care. Advances in molecular technology, including tissue and plasma next-generation sequencing (NGS), have led to the identification of new actionable molecular drivers and resistance mechanisms to targeted agents. Subsequently, new selective targeted therapies have been developed, and some have recently entered clinical practice based on substantial clinical benefit (e.g. selective MET inhibitors targeting MET exon 14 mutations). During this virtual satellite symposium, which is being held in conjunction with the 9th InterAmerican Oncology Conference, the expert panel will present the latest advances in optimizing biomarker detection in advanced non-small cell lung cancer (NSCLC) and strategies for treating patients with MET-altered NSCLC. A live discussion session will address questions from the audience.

This program is available to healthcare professionals who have registered for the 9th InterAmerican Oncology Conference.

Faculty

Luiz Henrique de Lima Araujo, MD, PhD

Luiz Henrique de Lima Araujo, MD, PhD | Moderator

Brazilian National Cancer Institute and COI Institute for Research & Education

Rio de Janeiro, Brazil

Dr Luiz Henrique de Lima Araujo received his medical degree from the Federal University of Minas Gerais, Brazil, in 2004. He completed his residency in Internal Medicine at the Julia Kubitschek Hospital – FHEMIG (2004 – 2006) and in Medical Oncology at the Brazilian National Cancer Institute (INCA, 2006 – 2008). He was awarded a fellowship in Cancer Research at INCA (2009 – 2011) and completed his Master of Science at INCA (2009 – 2011), and his PhD at the Federal University of Rio de Janeiro (2013 – 2016). Dr Araujo worked as a Medical Oncologist at INCA (2011 – 2012) serving in-patient care, teaching, and research, with a focus on lung and head & neck cancer. He is a former fellow of the American Society of Clinical Oncology, working as a post-doctoral researcher in translational projects on lung cancer genomics at The Ohio State University (Columbus, Ohio, USA) from 2012 to 2015. He is currently Physician-Scientist at INCA/Ministry of Health, with a focus on lung cancer genomics and other neoplasia. He also serves as Scientific Director at COI Institute for Research and Education, Oncology Coordinator at Samaritano Hospital, and Medical Advisor for Progenetica Laboratory / Pardini Group. Dr Araujo is an active member of ASCO, the American Association for Cancer Research, International Association for the Study of Lung Cancer (IASLC), and the Brazilian Society of Clinical Oncology (BSCO). He is the current President of SBOC-RJ and Secretary of AERINCA. Dr Araujo is a member of the International Committee for Lung Staging from IASLC and the Thoracic Oncology and Genomics from SBOC.

Paul Paik, MD

Paul Paik, MD

Thoracic Oncology Service

Memorial Sloan Kettering Cancer Center

New York, NY, United States

Paul K. Paik, MD is a medical oncologist at Memorial Sloan Kettering Cancer Center (MSKCC) who specializes in the treatment of lung cancers.  He is an Associate Attending Physician in the Thoracic Oncology Service at MSKCC, an Associate Professor of Medicine at Weill Cornell Medical College, and serves as the Clinical Director for the Thoracic Oncology Program at MSKCC. Dr. Paik’s research focuses on squamous cell lung cancer, targeted therapeutics, and translational therapies aimed at the metastatic process.

11:00        Welcome & introduction

11:03        Optimizing biomarker detection in advanced NSCLC: The role of NGS-based molecular testing

11:20        How I treat patients with MET-altered NSCLC.

11:37        Expert discussion and questions from the audience

11:47        Pearls for practice

This meeting is designed specifically for medical oncologists, pulmonologists, pathologists, and other clinicians involved in the management of patients with advanced NSCLC.

Upon completion of this educational activity, participants should be able to:

  • Assess the role of NGS-based tissue and liquid biopsy for the detection of uncommon molecular drivers in advanced NSCLC
  • Evaluate the optimal treatment strategies considering efficacy and safety for patients with MET exon 14 skipping mutations

Provided by ACE Oncology.

This educational activity is supported by an independent grant from the Healthcare business of Merck KGaA, Darmstadt, Germany.

The Faculty of Pharmaceutical Medicine has approved this event/course for CPD and allocated it 0.75 continuing professional development (CPD) credits.